The Role of Angiotensin II in the Pathogenesis of SARS-CoV-2

Corona Virus induced disease Covid-19 is an infectious disease caused by SARS-CoV-2 virus. People infected are likely to develop mild, moderate or severe illness and people suffering from chronic diseases are more likely to develop life-threatening complications.

We reviewed the literature of the last six months on manuscripts on SARS-CoV-2 during the first two waves of the pandemic.

Our manuscript describes viral transmission among humans through droplets of infected individuals and attempts to clarify the main pathogenetic mechanisms of this novel coronavirus. As there is not yet an approved treatment, we also present potential therapeutic targets including drugs of the renin angiotensin system.